First perform an X-ray and CAD4TB procedure, and reserve expensive tests like GeneXpert for patients with an X-ray suggestive of TB.
Delft Imaging Systems (Delft) is dedicated to improving people's quality of life around the world by means of its systems, software and services. Delft Imaging Systems aims to strengthen health care globally with affordable and innovative medical imaging solutions. As appropriate healthcare is a basic need,
Delft envisions a world in which we can all benefit from the modern world advances in the field of healthcare.
The National Tuberculosis Control Programme of Swaziland early 2016 ordered a mobile OneStopTB clinic to screen around 100,000 inhabitants in Swaziland on TB. The clinic enables the innovative TB screening algorithm with instant triage of suspects after screening based on digital X-ray empowered by CAD4TB (Computer Aided Detection software for TB). Patients presumptive of TB that have a CAD4TB score above a calculated threshold will be tested with the molecular GeneXpert MTB/RIF test, significantly reducing the time to detect and diagnose active TB to around 2 hours instead of days. The mobile OneStopTB clinic mounted on a truck is equipped with a DelftDI-Canon EasyDR X-ray, the latest version 5 of CAD4TB software and a separate laboratory with extraction hood and two GXP IV-4 machines. Installation of a CD4 counter for HIV/Aids infection is also foreseen, as over 80% of tuberculosis patients are also infected with HIV/AIDS. Powered by solar roof panels and batteries the CO2 neutral OneStopTB clinic can screen around 300 inhabitants per day without external electrical power. Screening will start in June after training of the highly motivated NTCP crew in Manzini, headed by Mr. Themba Dlamini and Dr. Welile Sikhondze. The project is funded by Global Fund and managed by NERCHA, the National Emergency Response Council on HIV/AIDS in Swaziland.
Early in 2015, the South African Health Minister and Chair of the Stop TB Partnership Coordinating Board, Dr Aaron Motsoaledi, announced that he was introducing 100% regular screening for tuberculosis for all inmates in South African prisons, as well as for their family members. The decision is significant given that rates of tuberculosis are considerably higher in prisons than within the general population. In September of 2015, The Union took a small group of South African and international journalists to visit Pollsmoor Prison on the outskirts of Cape Town in South Africa to observe the newly introduced South African screening policy. Pollsmoor was chosen because it was the prison where Nelson Mandela himself contracted tuberculosis while an inmate there for much of the 1980s. For the link to the original Union article published on the 17th of december 2015, please click here. The media responded by writing articles that appeared in The Guardian, Mail & Guardian, SABC News and elsewhere. The Union film about the screening of prisoners with CAD4TB can be viewed here.
The Union Centennial film, celebrating 100 Years of Know. Share. Act. Includes further information about the project.
The Baby Viewer is a unique ultrasound device that is ideally suited for use in those areas where big strides still need to be made in access to quality reproductive healthcare and the reduction of maternal mortality.
Philipsen, R. H. H. M., et al. "Automated chest-radiography as a triage for Xpert testing in resource-constrained settings: a prospective study of diagnostic accuracy and costs." Scientific reports 5 (2015). Abstract/PDF
Breuninger, Marianne, et al. "Diagnostic accuracy of computer-aided detection of pulmonary tuberculosis in chest radiographs: a validation study from sub-saharan Africa." (2014): e106381. Abstract/PDF
Melendez, Jaime, et al. "A Novel Multiple-Instance Learning-Based Approach to Computer-Aided Detection of Tuberculosis on Chest X-Rays." Medical Imaging, IEEE Transactions on 34.1 (2015): 179-192. Abstract/PDF
More CAD4TB Publications
With annually 9 million new cases and 1.5 million deaths worldwide, TB is the second cause of death after HIV/AIDS. Delft Imaging Systems' certified CAD4TB, Computer Aided Detection for TB, is a software package that automatically analyses chest X-rays and is capable of detecting abnormalities that may likely indicate TB. With Delft CAD4TB, skilled radiologists are no longer required to interpret chest X-rays enabling screening of remote populations in underserviced areas.